STARD3

Across TCGA patient cohorts, STARD3 mutation is significantly associated with the RNA expression of many other genes, with 2,611 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STARD3-associated genes across cancer lineages are RNA5SP421, RNA5SP415, and MIR6790. Each is linked with STARD3 in more than 2 cancer types. Because this analysis shows association rather than direction, both STARD3-to-partner and partner-to-STARD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP421 grouped by STARD3-low versus STARD3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STARD3→partner) and Y-score (partner→STARD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP421 →	+0.594	+2.063	<.001	<.001	3	3
UCEC	RNA5SP415 →	+0.544	+2.488	<.001	<.001	3	3
BRCA	MIR6790 →	+0.589	+7.133	<.001	<.001	3	2
BRCA	MIR6885 →	+0.456	+5.070	.004	.008	3	2
BRCA	MIR4646 →	+0.790	+5.409	<.001	.005	3	2
BLCA	OR7A8P →	+0.071	+4.463	.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,611 associations by consensus.

RNA5SP421 by STARD3 expression — UCEC

Explore this box plot interactively →