STARD3

Across TCGA cell cohorts, STARD3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,067 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible STARD3-associated GO terms across cancer lineages are Response to dehydroepiandrosterone, Protein depolymerization, and Response to epidermal growth factor. Each is linked with STARD3 in more than 12 cancer types. Because this analysis shows association rather than direction, both STARD3-to-partner and partner-to-STARD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to dehydroepiandrosterone grouped by STARD3-low versus STARD3-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (STARD3→partner) and Y-score (partner→STARD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Response to dehydroepiandrosterone →	+0.174	+0.838	<.001	.001	3	13
SKIN	Protein depolymerization →	+0.132	+1.130	<.001	<.001	3	11
URINARY_TRACT	Response to epidermal growth factor →	+0.096	+0.555	<.001	.001	3	11
LUNG_NSCLC_LUAD	Cellular response to epidermal growth factor stimulus →	+0.093	+0.734	<.001	<.001	3	11
LARGE_INTESTINE	Transcription pausing by RNA polymerase II →	+0.124	+1.477	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Negative regulation of DNA-templated transcription initiation →	+0.122	+1.235	<.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,067 associations by consensus.

Response to dehydroepiandrosterone by STARD3 expression — SOFT_TISSUE

Explore this box plot interactively →