STARD3

Across TCGA cell cohorts, STARD3 mutation is significantly associated with the RNA expression of many other genes, with 33 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible STARD3-associated genes across cancer lineages are SLC22A24, IFNA1, and SMIM9. Each is linked with STARD3 in more than 1 cancer types. Because this analysis shows association rather than direction, both STARD3-to-partner and partner-to-STARD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC22A24 grouped by STARD3-low versus STARD3-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STARD3→partner) and Y-score (partner→STARD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	SLC22A24 →	+0.013	+4.807	<.001	.006	3	1
BLOOD_Myeloma	IFNA1 →	+0.030	+4.807	<.001	.006	3	1
BLOOD_Myeloma	SMIM9 →	+0.020	+4.807	<.001	.006	3	1
LARGE_INTESTINE	TMCO2 →	+0.101	+4.347	<.001	.001	3	1
SKIN	OPALIN →	+0.072	+4.977	<.001	.007	3	1
SKIN	OR8K3 →	+0.073	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

SLC22A24 by STARD3 expression — BLOOD_Myeloma

Explore this box plot interactively →