STARD13

Across TCGA patient cohorts, STARD13 mutation is significantly associated with the total protein of many other genes, with 62 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STARD13-associated genes across cancer lineages are A-Raf_pS299, Caspase-7-cleavedD198, and Cyclin-B1. Each is linked with STARD13 in more than 2 cancer types. Because this analysis shows association rather than direction, both STARD13-to-partner and partner-to-STARD13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, A-Raf_pS299 grouped by STARD13-low versus STARD13-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STARD13→partner) and Y-score (partner→STARD13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	A-Raf_pS299 →	-0.105	-1.584	<.001	.007	3	3
UCEC	Caspase-7-cleavedD198 →	+0.590	+1.550	<.001	.002	3	3
UCEC	Cyclin-B1 →	+0.547	+2.201	<.001	<.001	3	3
UCEC	eEF2 →	+0.260	+2.247	.004	.001	3	2
UCEC	EGFR_pY1068 →	-0.212	-1.754	.001	<.001	3	2
COAD	eIF4E →	+0.226	+3.012	.004	.018	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 62 associations by consensus.

A-Raf_pS299 by STARD13 expression — UCEC

Explore this box plot interactively →