STAP2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, STAP2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,294 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible STAP2-associated genes across cancer lineages are UAP1, SH2D5, and SPINT1. Each is linked with STAP2 in more than 15 cancer types. Because this analysis shows association rather than direction, both STAP2-to-partner and partner-to-STAP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STAP2 versus UAP1 in BLOOD_Myeloma, with a Pearson correlation of 0.92.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STAP2→partner) and Y-score (partner→STAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_MyelomaUAP1 →+3.021+3.980.002<.001316
LUNG_NSCLC_LUSCSH2D5 →+2.409+2.119.005.00538
BLOOD_MyelomaSPINT1 →-4.265-3.687<.001<.00137
BLOOD_LymphomaTNFRSF12A →+2.602+2.491<.001<.00137
LUNG_NSCLC_LUADESRP1 →-2.540-1.123.009.00836
LUNG_NSCLC_LUSCNAV3 →+2.940+2.456<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,294 associations by consensus.

STAP2 vs UAP1 — BLOOD_Myeloma

Per-sample scatter of STAP2 vs UAP1 in BLOOD_Myeloma (Pearson r = 0.92).

Explore this scatter interactively →

Exploration