STAP1

Across TCGA patient cohorts, STAP1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,140 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible STAP1-associated genes across cancer lineages are PLEK, LILRB2, and SAMSN1. Each is linked with STAP1 in more than 3 cancer types. Because this analysis shows association rather than direction, both STAP1-to-partner and partner-to-STAP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STAP1 versus PLEK in BRCA, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STAP1→partner) and Y-score (partner→STAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PLEK →	+1.346	+1.144	<.001	<.001	3	4
BRCA	LILRB2 →	+1.153	+0.822	<.001	.005	3	4
HNSC	SAMSN1 →	+1.066	+0.878	<.001	<.001	3	4
HNSC	CD79A →	+2.939	+0.917	<.001	<.001	3	4
HNSC	POU2AF1 →	+1.921	+1.106	<.001	<.001	3	4
HNSC	LAX1 →	+1.412	+0.852	.004	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,140 associations by consensus.

STAP1 vs PLEK — BRCA

Explore this scatter interactively →