STAP1

Across TCGA cell cohorts, STAP1 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible STAP1-associated genes across cancer lineages are CT47A6, TBC1D21, and CCER1. Each is linked with STAP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both STAP1-to-partner and partner-to-STAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CT47A6 grouped by STAP1-low versus STAP1-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STAP1→partner) and Y-score (partner→STAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	CT47A6 →	+0.046	+5.285	<.001	.003	3	1
LARGE_INTESTINE	TBC1D21 →	+0.020	+6.022	<.001	.001	3	1
LARGE_INTESTINE	CCER1 →	+0.012	+4.977	<.001	.007	3	1
LARGE_INTESTINE	OR10R2 →	+0.031	+4.977	<.001	.007	3	1
LARGE_INTESTINE	PYDC2 →	+0.145	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

CT47A6 by STAP1 expression — STOMACH

Explore this box plot interactively →