STAMBPL1

Across TCGA patient cohorts, STAMBPL1 mutation is significantly associated with the RNA expression of many other genes, with 993 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STAMBPL1-associated genes across cancer lineages are UBTFL3, SYPL1P1, and RNA5SP422. Each is linked with STAMBPL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both STAMBPL1-to-partner and partner-to-STAMBPL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UBTFL3 grouped by STAMBPL1-low versus STAMBPL1-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STAMBPL1→partner) and Y-score (partner→STAMBPL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	UBTFL3 →	+0.079	+7.954	<.001	.008	3	2
UCEC	SYPL1P1 →	+0.104	+2.423	<.001	.004	3	2
UCEC	RNA5SP422 →	+0.929	+2.019	<.001	.005	3	2
SKCM	SLC25A20P1 →	+0.041	+3.817	<.001	.004	3	2
LUSC	SNX18P10 →	+0.111	+6.906	<.001	<.001	3	2
UCEC	LIN7C →	+0.589	+3.708	.003	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 993 associations by consensus.

UBTFL3 by STAMBPL1 expression — HNSC

Explore this box plot interactively →