STAMBPL1

Across TCGA cell cohorts, STAMBPL1 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible STAMBPL1-associated genes across cancer lineages are GTSF1L, TRIML1, and SRY. Each is linked with STAMBPL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both STAMBPL1-to-partner and partner-to-STAMBPL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GTSF1L grouped by STAMBPL1-low versus STAMBPL1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STAMBPL1→partner) and Y-score (partner→STAMBPL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	GTSF1L →	+0.045	+4.544	<.001	.003	3	1
LUNG_NSCLC_LUAD	TRIML1 →	+0.107	+4.371	<.001	.005	3	1
LUNG_NSCLC_LUAD	SRY →	+0.073	+4.544	<.001	.003	3	1
LARGE_INTESTINE	TTLL8 →	+0.002	+3.700	<.001	.009	3	1
LARGE_INTESTINE	TBC1D21 →	+0.008	+3.700	<.001	.009	3	1
LARGE_INTESTINE	OR10W1 →	+0.010	+3.562	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

GTSF1L by STAMBPL1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →