STAMBP

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, STAMBP mutation is significantly associated with the RNA expression of many other genes, with 447 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STAMBP-associated genes across cancer lineages are RPS26P56, OR5AW1P, and EZH2P1. Each is linked with STAMBP in more than 1 cancer types. Because this analysis shows association rather than direction, both STAMBP-to-partner and partner-to-STAMBP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPS26P56 grouped by STAMBP-low versus STAMBP-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STAMBP→partner) and Y-score (partner→STAMBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMRPS26P56 →+0.277+3.953<.001.00132
SKCMOR5AW1P →+0.035+4.233<.001.00132
SKCMEZH2P1 →+0.129+3.145<.001.00432
SKCMTPT1P7 →+0.219+3.241<.001.00332
UCECCHP1 →+0.409+2.087.008.00632
UCECSPRN →+0.430+2.831.006.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 447 associations by consensus.

RPS26P56 by STAMBP expression — SKCM

Box plot of RPS26P56 in STAMBP-low vs STAMBP-high samples in SKCM.

Explore this box plot interactively →

Exploration