STAMBP

Across TCGA patient cohorts, STAMBP mutation is significantly associated with the total protein of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STAMBP-associated genes across cancer lineages are Caspase-7-cleavedD198, mTOR_pS2448, and mTOR. Each is linked with STAMBP in more than 1 cancer types. Because this analysis shows association rather than direction, both STAMBP-to-partner and partner-to-STAMBP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by STAMBP-low versus STAMBP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STAMBP→partner) and Y-score (partner→STAMBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.524	+1.807	.032	.027	3	2
UCEC	mTOR_pS2448 →	-0.154	-1.861	.012	.049	3	1
UCEC	mTOR →	-0.208	-3.169	.001	.018	3	1
UCEC	Myosin-IIa →	+0.171	+2.010	.029	.017	3	1
UCEC	PCNA →	+0.216	+1.807	.015	.027	3	1
UCEC	PDK1_pS241 →	+0.165	+2.348	.019	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Caspase-7-cleavedD198 by STAMBP expression — UCEC

Explore this box plot interactively →