STAM2

Across TCGA cell cohorts, STAM2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,364 significant associations in total. CNS shows the largest number of these associations.

The most reproducible STAM2-associated GO terms across cancer lineages are Endosomal transport, Establishment of protein localization to vacuole, and Cytosolic transport. Each is linked with STAM2 in more than 17 cancer types. Because this analysis shows association rather than direction, both STAM2-to-partner and partner-to-STAM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosomal transport grouped by STAM2-low versus STAM2-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (STAM2→partner) and Y-score (partner→STAM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Endosomal transport →	+0.070	+1.019	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Establishment of protein localization to vacuole →	+0.085	+0.686	<.001	<.001	3	17
BONE	Cytosolic transport →	+0.082	+0.875	.002	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Protein localization to vacuole →	+0.075	+0.697	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Macroautophagy →	+0.072	+0.847	.002	.001	3	15
BREAST	Golgi vesicle transport →	+0.083	+0.954	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,364 associations by consensus.

Endosomal transport by STAM2 expression — BREAST

Explore this box plot interactively →