STAM2

Across TCGA cell cohorts, STAM2 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible STAM2-associated genes across cancer lineages are FTMT, OR2L8, and ACKR1. Each is linked with STAM2 in more than 1 cancer types. Because this analysis shows association rather than direction, both STAM2-to-partner and partner-to-STAM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FTMT grouped by STAM2-low versus STAM2-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STAM2→partner) and Y-score (partner→STAM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	FTMT →	+0.086	+5.977	<.001	.001	3	1
SOFT_TISSUE	OR2L8 →	+0.039	+5.369	<.001	.004	3	1
LARGE_INTESTINE	ACKR1 →	+0.054	+4.032	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

FTMT by STAM2 expression — SOFT_TISSUE

Explore this box plot interactively →