STAG3L5P-PVRIG2P-PILRB

Across TCGA pan-cancer cohorts, STAG3L5P-PVRIG2P-PILRB RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of STAG3L5P-PVRIG2P-PILRB’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where STAG3L5P-PVRIG2P-PILRB RNA is more highly expressed in tumor relative to normal tissue. In most cancer types STAG3L5P-PVRIG2P-PILRB is over-expressed in tumor, although a few such as KICH and BRCA show the opposite, repressed pattern.

KIRC, COAD, and LIHC are the cancer types where STAG3L5P-PVRIG2P-PILRB tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in STAG3L5P-PVRIG2P-PILRB RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	II,III,IV	+0.576	<.001	10	view →
COAD	Male	II,III,IV	+0.724	<.001	9	view →
LIHC	Female	II,III,IV	+0.565	<.001	9	view →
HNSC	Male	III,IV	+0.648	<.001	8	view →
KICH	All	All	−0.482	<.001	4	view →
STAD	All	All	+0.425	.002	4	view →
BRCA	Female	All	−0.336	<.001	4	view →
CHOL	All	All	+1.288	<.001	3	view →
ESCA	All	All	+0.601	.020	3	view →
LUSC	All	All	+0.338	.002	3	view →
READ	Female	All	+1.231	<.001	2	view →
BLCA	All	All	+0.417	.023	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

STAG3L5P-PVRIG2P-PILRB–KIRC

Open the KIRC breakdown →