STAG2

Across TCGA patient cohorts, STAG2 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,609 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible STAG2-associated proteins across cancer lineages are HNRNPH2, HCFC1, and UBE2J1. Each is linked with STAG2 in more than 7 cancer types. Because this analysis shows association rather than direction, both STAG2-to-partner and partner-to-STAG2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STAG2 versus HNRNPH2 in HNSC, with a Pearson correlation of 0.24.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (STAG2→partner) and Y-score (partner→STAG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	HNRNPH2 →	+0.207	+0.332	.003	.008	1	8
GBM	HCFC1 →	+0.323	+0.406	<.001	.001	3	6
BRCA	UBE2J1 →	-0.557	-0.494	<.001	.002	3	6
GBM	RAD21 →	+0.259	+0.400	<.001	<.001	3	6
LUAD	TCEAL4 →	+0.364	+0.410	<.001	<.001	3	6
GBM	TRIM24 →	+0.369	+0.340	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,609 associations by consensus.

STAG2 vs HNRNPH2 — HNSC

Explore this scatter interactively →