STAG1

Across TCGA patient cohorts, STAG1 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,028 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible STAG1-associated proteins across cancer lineages are BRD4, DBR1, and DEK. Each is linked with STAG1 in more than 5 cancer types. Because this analysis shows association rather than direction, both STAG1-to-partner and partner-to-STAG1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STAG1 versus BRD4 in HNSC, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (STAG1→partner) and Y-score (partner→STAG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	BRD4 →	+0.280	+0.614	<.001	<.001	3	6
LSCC	DBR1 →	+0.311	+0.571	<.001	<.001	3	6
UCEC	DEK →	+0.357	+0.541	<.001	<.001	3	6
GBM	GATAD2B →	+0.357	+0.368	<.001	<.001	3	6
HNSC	HCFC1 →	+0.258	+0.561	<.001	<.001	3	6
OV	MLYCD →	-0.389	-0.611	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,028 associations by consensus.

STAG1 vs BRD4 — HNSC

Explore this scatter interactively →