STAC3

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, STAC3 mutation is significantly associated with the RNA expression of many other genes, with 619 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STAC3-associated genes across cancer lineages are MIR8064, RNA5SP411, and MIR6077. Each is linked with STAC3 in more than 1 cancer types. Because this analysis shows association rather than direction, both STAC3-to-partner and partner-to-STAC3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STAC3→partner) and Y-score (partner→STAC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMIR8064 →+0.304+2.048<.001.00832
UCECRNA5SP411 →+0.891+2.071.002.00332
SKCMMIR6077 →+0.505+3.695<.001.00932
COADCDK8P1 →+0.230+4.026.003.00132
LUADRPL23AP84 →+0.194+5.523<.001<.00132
UCECRN7SL98P →+0.106+2.466.002.00432
Each partner links to its Q-omics profile. Showing the 6 strongest of 619 associations by consensus.

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