Across TCGA cell cohorts, STAC3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,584 significant associations in total. BONE shows the largest number of these associations.

The most reproducible STAC3-associated GO terms across cancer lineages are Positive regulation of DNA repair, Positive regulation of double-strand break repair, and Regulation of myoblast fusion. Each is linked with STAC3 in more than 12 cancer types. Because this analysis shows association rather than direction, both STAC3-to-partner and partner-to-STAC3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (STAC3→partner) and Y-score (partner→STAC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of DNA repair →	+0.072	+0.733	<.001	<.001	3	13
SOFT_TISSUE	Positive regulation of double-strand break repair →	+0.074	+3.648	.002	.002	3	13
OESOPHAGUS	Regulation of myoblast fusion →	+0.148	+0.735	<.001	.007	2	13
BONE	Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway →	+0.148	+0.889	<.001	<.001	3	11
SOFT_TISSUE	Chromatin looping →	+0.111	+4.421	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Taurine biosynthetic process →	+0.735	+0.303	.005	.002	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,584 associations by consensus.

Exploration

STAC3 survival (RNA) · tumor vs normal (RNA) · all STAC3 data types