STAC2

Across TCGA patient cohorts, STAC2 RNA expression is significantly associated with the RNA expression of many other genes, with 12,515 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible STAC2-associated genes across cancer lineages are CPAMD8, CACNB1, and JPH2. Each is linked with STAC2 in more than 18 cancer types. Because this analysis shows association rather than direction, both STAC2-to-partner and partner-to-STAC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STAC2 versus CPAMD8 in UVM, with a Pearson correlation of 0.53.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STAC2→partner) and Y-score (partner→STAC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UVM	CPAMD8 →	+1.483	+2.288	<.001	<.001	3	19
LGG	CACNB1 →	+0.974	+2.117	<.001	<.001	3	19
SARC	JPH2 →	+1.935	+1.532	<.001	<.001	3	18
KICH	MAP1B →	+1.854	+2.062	<.001	<.001	2	19
UCS	REEP2 →	+1.234	+1.716	.001	.002	2	19
READ	TSPAN2 →	+1.388	+0.206	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,515 associations by consensus.

STAC2 vs CPAMD8 — UVM

Explore this scatter interactively →