STAC2

Across TCGA patient cohorts, STAC2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,309 significant associations in total. GBM shows the largest number of these associations.

The most reproducible STAC2-associated genes across cancer lineages are FAM89A, GRM3, and EPHB6. Each is linked with STAC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both STAC2-to-partner and partner-to-STAC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STAC2 versus FAM89A in CCRCC, with a Pearson correlation of 0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STAC2→partner) and Y-score (partner→STAC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	FAM89A →	+1.014	+0.679	<.001	.001	3	2
GBM	GRM3 →	+0.975	+0.501	<.001	<.001	3	2
BRCA	EPHB6 →	+1.452	+0.696	<.001	<.001	3	2
BRCA	TRIM2 →	+1.106	+0.704	.001	.006	3	2
BRCA	TNNT2 →	+0.275	+0.575	.009	.003	3	2
BRCA	GTDC1 →	+0.515	+0.654	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,309 associations by consensus.

STAC2 vs FAM89A — CCRCC

Explore this scatter interactively →