STAC2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, STAC2 protein abundance is significantly associated with the protein abundance of many other proteins, with 7,018 significant associations in total. GBM shows the largest number of these associations.

The most reproducible STAC2-associated proteins across cancer lineages are SPTBN2, DDB2_S26, and DNTTIP1. Each is linked with STAC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both STAC2-to-partner and partner-to-STAC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STAC2 versus SPTBN2 in GBM, with a Pearson correlation of 0.43.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (STAC2→partner) and Y-score (partner→STAC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMSPTBN2 →+0.730+0.820<.001<.00132
BRCADDB2_S26 →-0.442-0.618<.001.00132
BRCADNTTIP1 →-0.435-0.950<.001<.00132
GBMEPB41L1_S564 →+0.841+0.571<.001<.00132
BRCAFBXO38 →-0.400-0.916.001<.00132
BRCAFLYWCH2 →-0.591-0.725<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,018 associations by consensus.

STAC2 vs SPTBN2 — GBM

Per-sample scatter of STAC2 vs SPTBN2 in GBM (Pearson r = 0.43).

Explore this scatter interactively →

Exploration