STAC2

Across TCGA cell cohorts, STAC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,334 significant associations in total. BONE shows the largest number of these associations.

The most reproducible STAC2-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Protein-DNA complex organization, and RNA splicing, via transesterification reactions. Each is linked with STAC2 in more than 8 cancer types. Because this analysis shows association rather than direction, both STAC2-to-partner and partner-to-STAC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by STAC2-low versus STAC2-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (STAC2→partner) and Y-score (partner→STAC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Negative regulation of myoblast fusion →	+0.082	+0.254	<.001	<.001	3	9
OVARY	Protein-DNA complex organization →	+0.039	+0.453	<.001	.006	3	9
BONE	RNA splicing, via transesterification reactions →	+0.062	+0.994	.003	.004	2	9
SKIN	Establishment of mitotic spindle localization →	+0.076	+0.270	.001	.007	3	8
OVARY	Regulation of transcription initiation by RNA polymerase II →	+0.044	+0.838	.004	.003	3	8
SKIN	Positive regulation of transcription initiation by RNA polymerase II →	+0.065	+0.329	<.001	.003	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,334 associations by consensus.

Negative regulation of myoblast fusion by STAC2 expression — SKIN

Explore this box plot interactively →