ST8SIA4

Across TCGA patient cohorts, ST8SIA4 protein abundance is significantly associated with the RNA expression of many other genes, with 1,151 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible ST8SIA4-associated genes across cancer lineages are SALL4, COQ7, and LYRM1. Each is linked with ST8SIA4 in more than 1 cancer types. Because this analysis shows association rather than direction, both ST8SIA4-to-partner and partner-to-ST8SIA4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ST8SIA4 versus SALL4 in GBM, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ST8SIA4→partner) and Y-score (partner→ST8SIA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SALL4 →	+1.160	+0.565	<.001	.002	3	2
GBM	COQ7 →	-0.637	-0.604	<.001	<.001	3	2
GBM	LYRM1 →	-0.515	-0.595	.001	<.001	3	1
GBM	VPS35L →	-0.324	-0.454	.006	.002	3	1
GBM	ANKMY2 →	-0.489	-0.515	.004	.002	3	1
GBM	RND2 →	-0.762	-0.393	.004	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,151 associations by consensus.

ST8SIA4 vs SALL4 — GBM

Explore this scatter interactively →