ST8SIA4

Across TCGA cell cohorts, ST8SIA4 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,848 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ST8SIA4-associated GO terms across cancer lineages are Oxidative phosphorylation, Energy derivation by oxidation of organic compounds, and ATP synthesis coupled electron transport. Each is linked with ST8SIA4 in more than 8 cancer types. Because this analysis shows association rather than direction, both ST8SIA4-to-partner and partner-to-ST8SIA4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Oxidative phosphorylation grouped by ST8SIA4-low versus ST8SIA4-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ST8SIA4→partner) and Y-score (partner→ST8SIA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Oxidative phosphorylation →	+0.075	+1.096	<.001	.003	3	8
SOFT_TISSUE	Energy derivation by oxidation of organic compounds →	+0.068	+1.442	<.001	.001	2	9
BLOOD_Lymphoma	ATP synthesis coupled electron transport →	+0.080	+1.271	<.001	<.001	3	8
BLOOD_Lymphoma	Mitochondrial ATP synthesis coupled electron transport →	+0.080	+1.271	<.001	<.001	3	8
SKIN	Aerobic electron transport chain →	+0.075	+0.872	<.001	.004	3	8
SKIN	Proton motive force-driven ATP synthesis →	+0.072	+0.850	.001	.006	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,848 associations by consensus.

Oxidative phosphorylation by ST8SIA4 expression — SOFT_TISSUE

Explore this box plot interactively →