ST8SIA4

Across TCGA cell cohorts, ST8SIA4 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible ST8SIA4-associated genes across cancer lineages are CCL7, OR13D1, and LCE1C. Each is linked with ST8SIA4 in more than 1 cancer types. Because this analysis shows association rather than direction, both ST8SIA4-to-partner and partner-to-ST8SIA4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCL7 grouped by ST8SIA4-low versus ST8SIA4-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ST8SIA4→partner) and Y-score (partner→ST8SIA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	CCL7 →	+0.376	+4.044	<.001	.009	3	1
LUNG_SCLC	OR13D1 →	+0.043	+4.269	<.001	.005	3	1
LUNG_SCLC	LCE1C →	+0.672	+4.643	<.001	.004	3	1
LUNG_SCLC	KPRP →	+0.438	+4.044	<.001	.009	3	1
LUNG_SCLC	LCE1F →	+0.107	+4.643	<.001	.004	3	1
SKIN	RBMY1J →	+0.006	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

CCL7 by ST8SIA4 expression — LUNG_SCLC

Explore this box plot interactively →