ST7L

Across TCGA pan-cancer cohorts, ST7L Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ST7L data layer compared with 28 for mass-spec protein and 1 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher ST7L Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated ST7L expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

UCEC, LIHC, and SKCM are the cancer types where ST7L Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	1.000	0.627	.015	14	view →
LIHC	DFS	Median	All	0.100	0.544	.003	12	view →
SKCM	OS	Median	III,IV	0.245	0.721	.018	12	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
CHOL	OS	Median	All	0.155	0.725	.029	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

ST7L–UCEC (DFS)

Open the UCEC breakdown →