ST7L

Across TCGA patient cohorts, ST7L mutation is significantly associated with the RNA expression of many other genes, with 1,461 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ST7L-associated genes across cancer lineages are MIR8082, COX6A1P2, and ITPK1. Each is linked with ST7L in more than 1 cancer types. Because this analysis shows association rather than direction, both ST7L-to-partner and partner-to-ST7L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR8082 grouped by ST7L-low versus ST7L-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ST7L→partner) and Y-score (partner→ST7L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR8082 →	+0.324	+2.059	<.001	.005	3	2
UCEC	COX6A1P2 →	+0.771	+1.880	<.001	.005	3	2
UCEC	ITPK1 →	+0.472	+3.617	<.001	.001	3	2
UCEC	BEX4 →	-1.477	-3.807	<.001	<.001	3	2
UCEC	NAPA →	+0.457	+2.301	.001	.001	3	2
UCEC	TMEM104 →	+0.465	+3.815	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,461 associations by consensus.

MIR8082 by ST7L expression — UCEC

Explore this box plot interactively →