ST7L

Across TCGA cell cohorts, ST7L RNA expression is significantly associated with the go_rna of many other GO terms, with 2,350 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ST7L-associated GO terms across cancer lineages are Telomeric 3' overhang formation, Centrosome cycle, and Zinc ion import into Golgi lumen. Each is linked with ST7L in more than 11 cancer types. Because this analysis shows association rather than direction, both ST7L-to-partner and partner-to-ST7L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Telomeric 3' overhang formation grouped by ST7L-low versus ST7L-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ST7L→partner) and Y-score (partner→ST7L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Telomeric 3' overhang formation →	+0.123	+0.733	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Centrosome cycle →	+0.064	+0.873	.005	<.001	3	9
LUNG_NSCLC_LUSC	Zinc ion import into Golgi lumen →	+0.114	+0.708	.001	.001	3	9
KIDNEY	Termination of RNA polymerase II transcription →	+0.107	+0.574	.004	.003	3	9
UPPER_AERODIGESTIVE_TRACT	Microtubule organizing center organization →	+0.068	+0.915	.002	<.001	3	8
SOFT_TISSUE	Negative regulation of protein ubiquitination →	+0.049	+0.620	.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,350 associations by consensus.

Telomeric 3' overhang formation by ST7L expression — OVARY

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