ST7L

Across TCGA cell cohorts, ST7L mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ST7L-associated genes across cancer lineages are OR52E5, SYT10, and ZSWIM2. Each is linked with ST7L in more than 1 cancer types. Because this analysis shows association rather than direction, both ST7L-to-partner and partner-to-ST7L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR52E5 grouped by ST7L-low versus ST7L-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ST7L→partner) and Y-score (partner→ST7L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR52E5 →	+0.016	+5.539	<.001	.003	3	1
SKIN	SYT10 →	+0.331	+3.632	<.001	.003	3	1
SKIN	ZSWIM2 →	+0.052	+3.196	.004	.007	3	1
SKIN	NOTO →	+0.024	+5.199	<.001	<.001	3	1
SKIN	OR5M11 →	+0.048	+4.022	<.001	.006	3	1
CNS	OR1E2 →	+0.341	+4.321	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

OR52E5 by ST7L expression — BLOOD_Leukemia

Explore this box plot interactively →