ST7

Across TCGA pan-cancer cohorts, ST7 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated ST7 data layer compared with 25 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher ST7 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated ST7 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

UCEC, HNSC, and CCRCC are the cancer types where ST7 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	0.988	0.783	.003	22	view →
HNSC	OS	Quartile	All	0.161	0.798	.045	12	view →
CCRCC	DFS	Quartile	III,IV	0.412	1.000	.045	2	view →
PDAC	DFS	Median	All	0.281	0.460	.028	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

ST7–UCEC (DFS)

Open the UCEC breakdown →