ST7

Across TCGA cell cohorts, ST7 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,935 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ST7-associated GO terms across cancer lineages are Regulation of membrane tubulation, Proton transmembrane transport, and Vesicle transport along actin filament. Each is linked with ST7 in more than 8 cancer types. Because this analysis shows association rather than direction, both ST7-to-partner and partner-to-ST7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of membrane tubulation grouped by ST7-low versus ST7-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ST7→partner) and Y-score (partner→ST7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Regulation of membrane tubulation →	+0.165	+0.766	<.001	<.001	3	9
SKIN	Proton transmembrane transport →	+0.070	+0.819	<.001	<.001	3	7
SKIN	Vesicle transport along actin filament →	+0.127	+0.999	<.001	<.001	3	7
BLOOD_Myeloma	DNA-templated transcription termination →	+0.076	+1.037	.005	.005	3	7
BONE	Cellular response to molecule of bacterial origin →	-0.053	-0.619	.002	.002	3	7
LARGE_INTESTINE	ATP synthesis coupled electron transport →	+0.065	+0.362	.001	.005	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,935 associations by consensus.

Regulation of membrane tubulation by ST7 expression — PANCREAS

Explore this box plot interactively →