ST6GAL2

Across TCGA patient cohorts, ST6GAL2 protein abundance is significantly associated with the RNA expression of many other genes, with 680 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ST6GAL2-associated genes across cancer lineages are CRYBB2P1, HIRA, and CYP2D6. Each is linked with ST6GAL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ST6GAL2-to-partner and partner-to-ST6GAL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ST6GAL2 versus CRYBB2P1 in GBM, with a Pearson correlation of 0.92.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ST6GAL2→partner) and Y-score (partner→ST6GAL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CRYBB2P1 →	+0.749	+0.810	.002	.003	3	1
GBM	HIRA →	+0.766	+0.810	.003	.003	3	1
GBM	CYP2D6 →	+1.586	+0.810	.001	.003	3	1
GBM	GTPBP1 →	+1.437	+0.810	.004	.003	3	1
GBM	SBF1 →	+1.257	+0.810	.006	.003	3	1
GBM	EP300 →	+1.199	+1.049	.007	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 680 associations by consensus.

ST6GAL2 vs CRYBB2P1 — GBM

Explore this scatter interactively →