ST6GAL2

Across TCGA patient cohorts, ST6GAL2 mutation is significantly associated with the RNA expression of many other genes, with 4,855 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible ST6GAL2-associated genes across cancer lineages are CENPU, CHAF1A, and RANBP1. Each is linked with ST6GAL2 in more than 4 cancer types. Because this analysis shows association rather than direction, both ST6GAL2-to-partner and partner-to-ST6GAL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CENPU grouped by ST6GAL2-low versus ST6GAL2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ST6GAL2→partner) and Y-score (partner→ST6GAL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	CENPU →	+0.526	+2.038	<.001	<.001	3	4
UCEC	CHAF1A →	+0.551	+2.136	<.001	<.001	3	4
LUAD	RANBP1 →	+0.479	+2.700	<.001	.005	3	4
UCEC	OIP5 →	+0.591	+1.606	.002	.003	3	4
LUAD	ZWINT →	+0.709	+1.819	<.001	.002	3	4
UCEC	PSMC3IP →	+0.498	+1.595	<.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,855 associations by consensus.

CENPU by ST6GAL2 expression — SKCM

Explore this box plot interactively →