ST6GAL2

Across TCGA cell cohorts, ST6GAL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,040 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ST6GAL2-associated GO terms across cancer lineages are Regulation of organelle assembly, Regulation of syncytium formation by plasma membrane fusion, and Microtubule organizing center organization. Each is linked with ST6GAL2 in more than 5 cancer types. Because this analysis shows association rather than direction, both ST6GAL2-to-partner and partner-to-ST6GAL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of organelle assembly grouped by ST6GAL2-low versus ST6GAL2-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ST6GAL2→partner) and Y-score (partner→ST6GAL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of organelle assembly →	+0.058	+1.789	<.001	.002	3	6
OVARY	Regulation of syncytium formation by plasma membrane fusion →	+0.084	+1.656	.002	<.001	3	5
SOFT_TISSUE	Microtubule organizing center organization →	+0.077	+1.783	<.001	<.001	3	5
UPPER_AERODIGESTIVE_TRACT	Positive regulation of double-strand break repair via homologous recombination →	+0.070	+0.044	<.001	.005	2	6
STOMACH	Transcription elongation by RNA polymerase II →	+0.082	+0.031	.001	.006	2	6
SOFT_TISSUE	mRNA export from nucleus →	+0.063	+1.493	.004	.003	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,040 associations by consensus.

Regulation of organelle assembly by ST6GAL2 expression — LUNG_SCLC

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