ST6GAL2

Across TCGA cell cohorts, ST6GAL2 mutation is significantly associated with the RNA expression of many other genes, with 279 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ST6GAL2-associated genes across cancer lineages are ACADM, FAM205A, and AVP. Each is linked with ST6GAL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ST6GAL2-to-partner and partner-to-ST6GAL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACADM grouped by ST6GAL2-low versus ST6GAL2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ST6GAL2→partner) and Y-score (partner→ST6GAL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ACADM →	+0.703	+3.169	.003	.009	3	2
LARGE_INTESTINE	FAM205A →	+0.012	+2.444	.007	.001	3	2
BREAST	AVP →	+0.028	+4.196	<.001	.006	3	2
OVARY	PBOV1 →	+0.043	+4.357	.009	.001	3	2
LARGE_INTESTINE	EIF3L →	+0.515	+3.087	.003	.006	3	1
LARGE_INTESTINE	L3MBTL2 →	+0.534	+3.502	.006	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 279 associations by consensus.

ACADM by ST6GAL2 expression — LARGE_INTESTINE

Explore this box plot interactively →