ST6GAL1

Across TCGA patient cohorts, ST6GAL1 protein abundance is significantly associated with the RNA expression of many other genes, with 17,601 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ST6GAL1-associated genes across cancer lineages are MZB1, PIM2, and IGKC. Each is linked with ST6GAL1 in more than 6 cancer types. Because this analysis shows association rather than direction, both ST6GAL1-to-partner and partner-to-ST6GAL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ST6GAL1 versus MZB1 in LSCC, with a Pearson correlation of 0.79.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ST6GAL1→partner) and Y-score (partner→ST6GAL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MZB1 →	+1.874	+0.920	<.001	<.001	3	7
LSCC	PIM2 →	+1.321	+0.876	<.001	<.001	3	6
BRCA	IGKC →	+3.003	+0.817	<.001	<.001	3	6
BRCA	IGKJ4 →	+2.937	+0.871	<.001	<.001	3	6
BRCA	IGKJ3 →	+2.409	+0.739	<.001	<.001	3	6
BRCA	IGKV3D-11 →	+1.879	+0.647	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,601 associations by consensus.

ST6GAL1 vs MZB1 — LSCC

Explore this scatter interactively →