ST6GAL1

Across TCGA patient cohorts, ST6GAL1 mutation is significantly associated with the RNA expression of many other genes, with 2,718 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ST6GAL1-associated genes across cancer lineages are OR4F28P, MIR4445, and LINC01309. Each is linked with ST6GAL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ST6GAL1-to-partner and partner-to-ST6GAL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4F28P grouped by ST6GAL1-low versus ST6GAL1-high in SARC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ST6GAL1→partner) and Y-score (partner→ST6GAL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SARC	OR4F28P →	+0.069	+5.778	<.001	.003	3	2
UCEC	MIR4445 →	+0.118	+3.834	<.001	.007	3	2
CESC	LINC01309 →	+0.185	+5.164	<.001	.002	3	2
CESC	RNA5SP73 →	+0.301	+4.837	<.001	.003	3	2
CESC	RNA5SP53 →	+0.209	+3.411	.002	.009	3	2
SKCM	ASS1P8 →	+0.035	+4.302	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,718 associations by consensus.

OR4F28P by ST6GAL1 expression — SARC

Explore this box plot interactively →