ST6GAL1

Across TCGA cell cohorts, ST6GAL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,195 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ST6GAL1-associated GO terms across cancer lineages are mRNA stabilization, Negative regulation of mRNA metabolic process, and Ribosome localization. Each is linked with ST6GAL1 in more than 9 cancer types. Because this analysis shows association rather than direction, both ST6GAL1-to-partner and partner-to-ST6GAL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA stabilization grouped by ST6GAL1-low versus ST6GAL1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ST6GAL1→partner) and Y-score (partner→ST6GAL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	mRNA stabilization →	+0.072	+1.461	<.001	.003	3	10
STOMACH	Negative regulation of mRNA metabolic process →	+0.078	+1.842	.007	.004	3	9
OVARY	Ribosome localization →	+0.127	+1.978	<.001	<.001	3	9
OVARY	Ribosomal subunit export from nucleus →	+0.127	+1.978	<.001	<.001	3	9
BONE	Negative regulation of RNA catabolic process →	+0.067	+2.485	.003	.001	3	9
SOFT_TISSUE	RNA stabilization →	+0.093	+1.432	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,195 associations by consensus.

mRNA stabilization by ST6GAL1 expression — OVARY

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