ST6GAL1

Across TCGA cell cohorts, ST6GAL1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ST6GAL1-associated genes across cancer lineages are OR56A1, SLC15A5, and FAM205A. Each is linked with ST6GAL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ST6GAL1-to-partner and partner-to-ST6GAL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR56A1 grouped by ST6GAL1-low versus ST6GAL1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ST6GAL1→partner) and Y-score (partner→ST6GAL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR56A1 →	+0.012	+4.467	.005	.004	3	1
LARGE_INTESTINE	SLC15A5 →	+0.017	+4.415	<.001	.007	3	1
LARGE_INTESTINE	FAM205A →	+0.041	+4.614	<.001	.002	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

OR56A1 by ST6GAL1 expression — LARGE_INTESTINE

Explore this box plot interactively →