ST3GAL2

Across TCGA cell cohorts, ST3GAL2 mutation is significantly associated with the mutation status of many other genes, with 3,302 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ST3GAL2-associated genes across cancer lineages are GBF1, IGSF21, and PIK3C2B. Each is linked with ST3GAL2 in more than 2 cancer types. Because this analysis shows association rather than direction, both ST3GAL2-to-partner and partner-to-ST3GAL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GBF1 grouped by ST3GAL2-low versus ST3GAL2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ST3GAL2→partner) and Y-score (partner→ST3GAL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	GBF1 →	+2.498	+2.624	.008	.008	1	3
BLOOD_Lymphoma	IGSF21 →	+6.014	+6.014	.001	.001	1	3
BLOOD_Leukemia	PIK3C2B →	+3.235	+3.347	<.001	<.001	1	3
BLOOD_Leukemia	CACNA1D →	+2.498	+3.502	<.001	<.001	1	2
BLOOD_Leukemia	AUTS2 →	+2.498	+2.847	.002	.002	1	2
BLOOD_Leukemia	MCM3AP →	+2.498	+3.502	<.001	<.001	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,302 associations by consensus.

GBF1 by ST3GAL2 expression — BLOOD_Leukemia

Explore this box plot interactively →