ST3GAL2

Across TCGA cell cohorts, ST3GAL2 mutation is significantly associated with the drug of many other genes, with 17 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ST3GAL2-associated genes across cancer lineages are AZD8055, Bleomycin (10 uM), and IAP_5620. Each is linked with ST3GAL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ST3GAL2-to-partner and partner-to-ST3GAL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AZD8055 grouped by ST3GAL2-low versus ST3GAL2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ST3GAL2→partner) and Y-score (partner→ST3GAL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	AZD8055 →	-0.369	-2.819	.029	.029	3	1
BLOOD_Leukemia	Bleomycin (10 uM) →	+0.520	+3.000	.022	.028	3	1
BLOOD_Leukemia	IAP_5620 →	+0.788	+2.854	.001	.026	3	1
BLOOD_Leukemia	I-BET-762 →	-0.408	-3.000	.020	.028	3	1
BLOOD_Leukemia	TAF1_5496 →	+0.444	+2.999	.016	.026	3	1
BLOOD_Leukemia	JQ1 →	-0.538	-2.890	.017	.029	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

AZD8055 by ST3GAL2 expression — BLOOD_Leukemia

Explore this box plot interactively →