ST3GAL1P1

Across TCGA pan-cancer cohorts, ST3GAL1P1 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated ST3GAL1P1 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher ST3GAL1P1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ST3GAL1P1 expression acts as an unfavorable survival marker, although some lineages such as ESCA and PAAD show a favorable association.

UVM, ESCA, and PAAD are the cancer types where ST3GAL1P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Median	III,IV	0.346	0.727	.005	55	view →
ESCA	DFS	Median	II,III,IV	0.468	0.250	.003	33	view →
PAAD	OS	Quartile	II,III,IV	0.517	0.196	<.001	25	view →
UCS	DFS	Median	IV	0.952	0.367	.001	24	view →
LGG	DFS	Median	All	0.782	0.880	<.001	23	view →
PCPG	OS	Quartile	All	0.837	1.000	.007	23	view →
READ	OS	Tertile	All	0.940	0.681	.003	22	view →
LUSC	DFS	Tertile	III,IV	0.226	0.524	.009	20	view →
LIHC	OS	Quartile	All	0.648	0.823	.003	20	view →
UCEC	DFS	Quartile	II,III,IV	0.571	0.782	.002	16	view →
CHOL	OS	Median	All	0.876	0.161	<.001	15	view →
CESC	DFS	Median	III,IV	0.228	0.628	.003	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

ST3GAL1P1–UVM (DFS)

Open the UVM breakdown →