Across TCGA pan-cancer cohorts, ST3GAL1 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated ST3GAL1 data layer compared with 24 for mass-spec protein and 5 for mass-spec protein.
The strongest signal is observed in lung adenocarcinoma (LUAD), where higher ST3GAL1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ST3GAL1 expression acts as an unfavorable survival marker.
LUAD are the cancer types where ST3GAL1 Mutation most reproducibly stratifies survival.