ST3GAL1

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, ST3GAL1 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated ST3GAL1 data layer compared with 24 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher ST3GAL1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ST3GAL1 expression acts as an unfavorable survival marker.

LUAD are the cancer types where ST3GAL1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUADOSMedianAll0.3930.676.0372view →
Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

ST3GAL1–LUAD (OS)

Kaplan–Meier survival curve for ST3GAL1 mutant vs wild-type samples in LUAD.

Open the LUAD breakdown →

Exploration