ST13

Across TCGA pan-cancer cohorts, ST13 mass-spec protein differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of ST13’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where ST13 mass-spec protein is repressed in tumor relative to normal tissue. In most cancer types ST13 is over-expressed in tumor, although a few such as COAD and HNSC show the opposite, repressed pattern.

COAD, LSCC, and HNSC are the cancer types where ST13 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ST13 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Male	III,IV	−0.544	<.001	10	view →
LSCC	Male	All	+0.291	<.001	6	view →
HNSC	All	All	−0.126	.035	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

ST13–COAD

Open the COAD breakdown →