ST13

Across TCGA cell cohorts, ST13 mutation is significantly associated with the mutation status of many other genes, with 2,772 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ST13-associated genes across cancer lineages are ZBED4, LENG1, and HLX. Each is linked with ST13 in more than 2 cancer types. Because this analysis shows association rather than direction, both ST13-to-partner and partner-to-ST13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZBED4 grouped by ST13-low versus ST13-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ST13→partner) and Y-score (partner→ST13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	ZBED4 →	+4.429	+5.247	.005	.005	1	3
BLOOD_Lymphoma	LENG1 →	+6.014	+6.014	.001	.001	1	3
BLOOD_Lymphoma	HLX →	+5.014	+5.584	.003	.003	1	3
BLOOD_Lymphoma	DIP2A →	+4.014	+4.969	.008	.008	1	3
BLOOD_Leukemia	ZNF395 →	+5.894	+5.321	.002	.002	1	3
BLOOD_Lymphoma	CR1 →	+4.429	+5.247	.005	.005	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,772 associations by consensus.

ZBED4 by ST13 expression — BLOOD_Lymphoma

Explore this box plot interactively →