SSX4

Across TCGA patient cohorts, SSX4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,091 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SSX4-associated GO terms across cancer lineages are Apoptotic mitochondrial changes, Positive regulation of intracellular protein transport, and DNA strand elongation involved in DNA replication. Each is linked with SSX4 in more than 5 cancer types. Because this analysis shows association rather than direction, both SSX4-to-partner and partner-to-SSX4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Apoptotic mitochondrial changes grouped by SSX4-low versus SSX4-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SSX4→partner) and Y-score (partner→SSX4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Apoptotic mitochondrial changes →	+0.075	+0.105	<.001	<.001	3	6
UCEC	Positive regulation of intracellular protein transport →	+0.065	+0.013	<.001	<.001	3	5
UCEC	DNA strand elongation involved in DNA replication →	+0.074	+0.013	<.001	.003	3	5
STAD	Positive regulation of metaphase/anaphase transition of cell cycle →	+0.079	+0.070	<.001	<.001	3	5
UCEC	Regulation of organelle assembly →	+0.062	+0.010	<.001	.003	2	6
STAD	Positive regulation of mitotic cytokinesis →	+0.099	+0.142	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,091 associations by consensus.

Apoptotic mitochondrial changes by SSX4 expression — STAD

Explore this box plot interactively →