SSX4

Across TCGA cell cohorts, SSX4 RNA expression is significantly associated with the go_rna of many other GO terms, with 336 significant associations in total. CNS shows the largest number of these associations.

The most reproducible SSX4-associated GO terms across cancer lineages are Nuclear transport, Nucleocytoplasmic transport, and Regulation of protein localization to Cajal body. Each is linked with SSX4 in more than 4 cancer types. Because this analysis shows association rather than direction, both SSX4-to-partner and partner-to-SSX4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear transport grouped by SSX4-low versus SSX4-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SSX4→partner) and Y-score (partner→SSX4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Nuclear transport →	+0.066	+0.026	<.001	.008	3	5
PANCREAS	Nucleocytoplasmic transport →	+0.065	+0.026	<.001	.008	3	5
KIDNEY	Regulation of protein localization to Cajal body →	+0.033	+0.026	.004	.001	3	4
KIDNEY	Positive regulation of protein localization to Cajal body →	+0.033	+0.026	.004	.001	3	4
PANCREAS	Signal transduction in response to DNA damage →	+0.048	+0.030	<.001	<.001	3	4
SOFT_TISSUE	Cytoskeleton-dependent cytokinesis →	+0.045	+0.041	.004	.006	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 336 associations by consensus.

Nuclear transport by SSX4 expression — PANCREAS

Explore this box plot interactively →