SSX2IP

Across TCGA pan-cancer cohorts, SSX2IP mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated SSX2IP data layer compared with 24 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher SSX2IP mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated SSX2IP expression acts as an unfavorable survival marker, although some lineages such as LSCC and LUAD show a favorable association.

LSCC, LUAD, and HNSC are the cancer types where SSX2IP mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Quartile	All	0.884	0.410	.001	17	view →
LUAD	DFS	Median	All	0.783	0.354	.010	5	view →
HNSC	DFS	Median	III,IV	1.000	0.896	.048	2	view →
CCRCC	DFS	Tertile	All	1.000	0.780	.045	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

SSX2IP–LSCC (DFS)

Open the LSCC breakdown →