SSX2IP

Across TCGA patient cohorts, SSX2IP mutation is significantly associated with the RNA expression of many other genes, with 4,722 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SSX2IP-associated genes across cancer lineages are RN7SL519P, RNU1-57P, and SEPTIN14P2. Each is linked with SSX2IP in more than 1 cancer types. Because this analysis shows association rather than direction, both SSX2IP-to-partner and partner-to-SSX2IP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL519P grouped by SSX2IP-low versus SSX2IP-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SSX2IP→partner) and Y-score (partner→SSX2IP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RN7SL519P →	+0.159	+5.539	<.001	.004	3	2
STAD	RNU1-57P →	+0.725	+5.026	<.001	.009	3	2
STAD	SEPTIN14P2 →	+0.214	+5.463	<.001	.005	3	2
UCEC	TMEM138 →	+0.217	+1.885	.001	<.001	3	2
UCEC	SEC13 →	+0.463	+1.874	<.001	<.001	3	2
UCEC	EXOG →	+0.351	+1.678	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,722 associations by consensus.

RN7SL519P by SSX2IP expression — CESC

Explore this box plot interactively →