SSX1

Across TCGA pan-cancer cohorts, SSX1 Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated SSX1 data layer compared with 18 for mass-spec protein.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher SSX1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated SSX1 expression acts as an unfavorable survival marker.

BLCA, STAD, and GBM are the cancer types where SSX1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Median	All	0.120	0.720	<.001	48	view →
STAD	OS	Median	II,III,IV	0.183	0.677	.004	24	view →
GBM	OS	Median	All	0.005	0.416	<.001	12	view →
COAD	OS	Median	All	0.168	0.806	.002	12	view →
LIHC	OS	Median	All	0.098	0.774	.001	6	view →
SARC	DFS	Median	All	0.121	0.591	.042	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

SSX1–BLCA (OS)

Open the BLCA breakdown →